A1 Refereed original research article in a scientific journal
Cardiac hybrid imaging
Authors: Gaemperli O, Saraste A, Knuuti J
Publisher: OXFORD UNIV PRESS
Publication year: 2012
Journal: EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
Journal name in source: EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
Journal acronym: EUR HEART J-CARD IMG
Number in series: 1
Volume: 13
Issue: 1
First page : 51
Last page: 60
Number of pages: 10
ISSN: 2047-2404
DOI: https://doi.org/10.1093/ehjci/jer240
Abstract
Cardiac hybrid imaging combines different imaging modalities in a way where both modalities equally contribute to image information. The most common and best- studied approach is to combine computed tomography coronary angiography (CTCA) and myocardial perfusion imaging either with single- photon emission computed tomography or with positron emission tomography (PET). This combination is a promising tool for evaluation of coronary artery disease since it allows visualization of coronary atherosclerotic lesions and their haemodynamic consequences in a single study and it appears to offer superior diagnostic accuracy when compared with stand- alone imaging. More recent applications are a combination of CTCA and cardiac magnetic resonance imaging by using software image fusion and utilization of commercially available hybrid PET/MRI scanners for cardiac applications. Currently, these methods have been reported only as case reports, but several potential applications also in cardiology can be anticipated. The development of new molecular imaging probes will also open completely new possibilities for guidance and monitoring of advanced therapies. This review will focus on the concepts and currently available clinical experiences from cardiac hybrid imaging as well as discuss the potential future applications.
Cardiac hybrid imaging combines different imaging modalities in a way where both modalities equally contribute to image information. The most common and best- studied approach is to combine computed tomography coronary angiography (CTCA) and myocardial perfusion imaging either with single- photon emission computed tomography or with positron emission tomography (PET). This combination is a promising tool for evaluation of coronary artery disease since it allows visualization of coronary atherosclerotic lesions and their haemodynamic consequences in a single study and it appears to offer superior diagnostic accuracy when compared with stand- alone imaging. More recent applications are a combination of CTCA and cardiac magnetic resonance imaging by using software image fusion and utilization of commercially available hybrid PET/MRI scanners for cardiac applications. Currently, these methods have been reported only as case reports, but several potential applications also in cardiology can be anticipated. The development of new molecular imaging probes will also open completely new possibilities for guidance and monitoring of advanced therapies. This review will focus on the concepts and currently available clinical experiences from cardiac hybrid imaging as well as discuss the potential future applications.
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