MicroRNA-155 modulates P2R signaling and Th2 priming of dendritic cells during allergic airway inflammation in mice

: Zech A, Ayata CK, Pankratz F, Meyer A, Baudiss K, Cicko S, Yegutkin GG, Grundmann S, Idzko M

Publisher: WILEY-BLACKWELL

: Freiburg

: 2015

: Allergy

: ALLERGY

: 70

: 9

: 1121

: 1129

: 9

: 0105-4538

DOI: https://doi.org/10.1111/all.12643

ConclusionsmiR-155 deficiency alleviates AAI by diminishing Th2 priming capacity and ATP-/P2R-induced activation of DCs in mice, suggesting this miRNA as a potential therapeutic target of AAI.