Microbial Exposure in Infancy and Subsequent Appearance of Type 1 Diabetes Mellitus-Associated Autoantibodies – A Cohort Study - UTU Research Portal

A1 Refereed original research article in a scientific journal

Microbial Exposure in Infancy and Subsequent Appearance of Type 1 Diabetes Mellitus-Associated Autoantibodies – A Cohort Study

Subtitle: A Cohort Study

Authors: Suvi M. Virtanen, Hanna-Mari Takkinen, Bright I. Nwaru, Minna Kaila, Suvi Ahonen, Jaakko Nevalainen, Sari Niinistö, Heli Siljander, Olli Simell, Jorma Ilonen, Heikki Hyöty, Riitta Veijola, Mikael Knip

Publisher: AMER MEDICAL ASSOC

Publication year: 2014

Journal: JAMA Pediatrics

Journal name in source: JAMA PEDIATRICS

Journal acronym: JAMA PEDIATR

Volume: 168

Issue: 8

First page : 755

Last page: 763

Number of pages: 9

ISSN: 2168-6203

DOI: https://doi.org/10.1001/jamapediatrics.2014.296

Abstract

CONCLUSIONS AND RELEVANCE Among the 9 early microbial exposures studied, only the indoor dog exposure during the first year of life was inversely associated with the development of preclinical type 1 diabetes. This finding needs to be confirmed in other populations.