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Yersinia specific immune complexes in the synovial fluid of patients with yersinia triggered reactive arthritis
Tekijät: Lahesmaa-Rantala R, Granfors K, Isomäki H, Toivanen A
Julkaisuvuosi: 1987
Journal: Annals of the Rheumatic Diseases
Tietokannassa oleva lehden nimi: Annals of the rheumatic diseases
Lehden akronyymi: Ann Rheum Dis
Vuosikerta: 46
Numero: 7
Aloitussivu: 510
Lopetussivu: 4
Sivujen määrä: 5
ISSN: 0003-4967
DOI: https://doi.org/10.1136/ard.46.7.510
Tiivistelmä
Yersinia specific immune complexes were demonstrated in the synovial fluid of three patients out of 12 with yersinia triggered reactive arthritis. They were not detectable in the synovial fluid of any of the 16 control patients, including nine with reactive arthritis triggered by factors other than yersiniae. Platelet reactive IgG was detectable in the synovial fluid of eight out of the 12 patients with yersinia triggered reactive arthritis and in three of the 16 control patients, all three having rheumatoid arthritis. An enzyme linked immunosorbent assay and a platelet 125I labelled staphylococcal protein A test were used to measure yersinia specific immune complexes and platelet reactive IgG respectively. The results obtained show for the first time the occurrence of bacterial antigens, derived from the causative strain, in the synovial fluid in yersinia triggered reactive arthritis.
Yersinia specific immune complexes were demonstrated in the synovial fluid of three patients out of 12 with yersinia triggered reactive arthritis. They were not detectable in the synovial fluid of any of the 16 control patients, including nine with reactive arthritis triggered by factors other than yersiniae. Platelet reactive IgG was detectable in the synovial fluid of eight out of the 12 patients with yersinia triggered reactive arthritis and in three of the 16 control patients, all three having rheumatoid arthritis. An enzyme linked immunosorbent assay and a platelet 125I labelled staphylococcal protein A test were used to measure yersinia specific immune complexes and platelet reactive IgG respectively. The results obtained show for the first time the occurrence of bacterial antigens, derived from the causative strain, in the synovial fluid in yersinia triggered reactive arthritis.
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