Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2)
Immunological and bacteriological aspects of reactive arthritis
Julkaisun tekijät: Toivanen A, Granfors K, Lahesmaa-Rantala R, Toivanen P
Julkaisuvuosi: 1989
Journal: Rheumatology International
Tietokannassa oleva lehden nimi: Rheumatology international
Lehden akronyymi: Rheumatol Int
Volyymi: 9
Julkaisunumero: 3-5
Aloitussivu: 201
Lopetussivun numero: 3
Sivujen määrä: 3
ISSN: 0172-8172
Tiivistelmä
It is apparent that in the development of reactive arthritis the patient fails in his first line of defence against the invading microorganism. This results in persistence of the microorganism probably in or close to the intestinal epithelium. Microbial antigens may appear also in the circulation, perhaps as part of the immune complexes, or within cellular elements. Through these transportation mechanisms they enter the synovium, triggering an inflammatory process that leads to reactive arthritis.
It is apparent that in the development of reactive arthritis the patient fails in his first line of defence against the invading microorganism. This results in persistence of the microorganism probably in or close to the intestinal epithelium. Microbial antigens may appear also in the circulation, perhaps as part of the immune complexes, or within cellular elements. Through these transportation mechanisms they enter the synovium, triggering an inflammatory process that leads to reactive arthritis.