A1 Refereed original research article in a scientific journal
Bacterial antigens in synovial biopsy specimens in yersinia triggered reactive arthritis
Authors: Merilahti-Palo R, Söderström KO, Lahesmaa-Rantala R, Granfors K, Toivanen A
Publication year: 1991
Journal: Annals of the Rheumatic Diseases
Journal name in source: Annals of the rheumatic diseases
Journal acronym: Ann Rheum Dis
Volume: 50
Issue: 2
First page : 87
Last page: 90
Number of pages: 4
ISSN: 0003-4967
DOI: https://doi.org/10.1136/ard.50.2.87
Abstract
Non-viable structures of Yersinia enterocolitica O:3 were shown at the site of inflammation within mononuclear cells in the synovial membrane of eight out of 10 patients with yersinia triggered reactive arthritis. An avidin-biotin-peroxidase complex method, with a rabbit antiserum specific for Y enterocolitica O:3, was used to visualise yersinia structures. All 13 control samples were negative except for one with non-specific mast cell staining. The findings emphasise the significance of foreign material in the initiation of synovitis in reactive arthritis.
Non-viable structures of Yersinia enterocolitica O:3 were shown at the site of inflammation within mononuclear cells in the synovial membrane of eight out of 10 patients with yersinia triggered reactive arthritis. An avidin-biotin-peroxidase complex method, with a rabbit antiserum specific for Y enterocolitica O:3, was used to visualise yersinia structures. All 13 control samples were negative except for one with non-specific mast cell staining. The findings emphasise the significance of foreign material in the initiation of synovitis in reactive arthritis.
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