A1 Refereed original research article in a scientific journal

Group A streptococcal outbreak of perianal infection in a day-care centre




AuthorsMuotiala A, Saxén H, Vuopio-Varkila J

Publication year1997

JournalAdvances in Experimental Medicine and Biology

Journal name in sourceAdvances in experimental medicine and biology

Journal acronymAdv Exp Med Biol

Volume418

First page 211

Last page5

Number of pages5

ISBN0-306-45603-6

ISSN0065-2598


Abstract
Within 9 days in a day-care centre of 20 children 3 cases and 2 suspected cases of perianal infection (PAI) were revealed. The causative agent for PAI was confirmed to be beta-haemolytic group A streptococcus (GAS). The isolates were further characterized by T- and M-serotyping, conventional restriction endonuclease analysis (REA) and pulsed field gel electrophoresis (PFGE). The typing methods revealed that all outbreak isolates were of same T28R28-serotype and genetically identical. Unrelated, control GAS isolates of the same serotype differed genetically from the outbreak isolates indicating that a single clone had caused the perianal infections.



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