A1 Refereed original research article in a scientific journal
Group A streptococcal outbreak of perianal infection in a day-care centre
Authors: Muotiala A, Saxén H, Vuopio-Varkila J
Publication year: 1997
Journal:: Advances in Experimental Medicine and Biology
Journal name in source: Advances in experimental medicine and biology
Journal acronym: Adv Exp Med Biol
Volume: 418
First page : 211
Last page: 5
Number of pages: 5
ISBN: 0-306-45603-6
ISSN: 0065-2598
Abstract
Within 9 days in a day-care centre of 20 children 3 cases and 2 suspected cases of perianal infection (PAI) were revealed. The causative agent for PAI was confirmed to be beta-haemolytic group A streptococcus (GAS). The isolates were further characterized by T- and M-serotyping, conventional restriction endonuclease analysis (REA) and pulsed field gel electrophoresis (PFGE). The typing methods revealed that all outbreak isolates were of same T28R28-serotype and genetically identical. Unrelated, control GAS isolates of the same serotype differed genetically from the outbreak isolates indicating that a single clone had caused the perianal infections.
Within 9 days in a day-care centre of 20 children 3 cases and 2 suspected cases of perianal infection (PAI) were revealed. The causative agent for PAI was confirmed to be beta-haemolytic group A streptococcus (GAS). The isolates were further characterized by T- and M-serotyping, conventional restriction endonuclease analysis (REA) and pulsed field gel electrophoresis (PFGE). The typing methods revealed that all outbreak isolates were of same T28R28-serotype and genetically identical. Unrelated, control GAS isolates of the same serotype differed genetically from the outbreak isolates indicating that a single clone had caused the perianal infections.
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