A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Comparison of genotypes of methicillin-resistant and methicillin-sensitive Staphylococcus aureus in Finland
Tekijät: Ibrahem S, Salmenlinna S, Kerttula AM, Virolainen-Julkunen A, Kuusela P, Vuopio-Varkila J
Julkaisuvuosi: 2005
Journal: European Journal of Clinical Microbiology and Infectious Diseases
Tietokannassa oleva lehden nimi: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Lehden akronyymi: Eur J Clin Microbiol Infect Dis
Vuosikerta: 24
Numero: 5
Aloitussivu: 325
Lopetussivu: 8
Sivujen määrä: 4
ISSN: 0934-9723
DOI: https://doi.org/10.1007/s10096-005-1328-4
Tiivistelmä
The frequency of horizontal transfer of the staphylococcal cassette chromosome mec to methicillin-susceptible Staphylococcus aureus is unknown. In order to gain more information regarding this frequency in Finland, the genotypes of 299 clinical methicillin-sensitive Staphylococcus aureus isolates were compared to representatives of 24 epidemic methicillin-resistant Staphylococcus aureus genotypes. Sixty-eight percent of the methicillin-sensitive isolates had a genotype similar to eight of the epidemic methicillin-resistant strains. The remaining isolates (32%) showed 22 different genotypes. The results indicate that, in Finland, several methicillin-sensitive Staphylococcus aureus genotypes may have acquired the staphylococcal cassette chromosome mec.
The frequency of horizontal transfer of the staphylococcal cassette chromosome mec to methicillin-susceptible Staphylococcus aureus is unknown. In order to gain more information regarding this frequency in Finland, the genotypes of 299 clinical methicillin-sensitive Staphylococcus aureus isolates were compared to representatives of 24 epidemic methicillin-resistant Staphylococcus aureus genotypes. Sixty-eight percent of the methicillin-sensitive isolates had a genotype similar to eight of the epidemic methicillin-resistant strains. The remaining isolates (32%) showed 22 different genotypes. The results indicate that, in Finland, several methicillin-sensitive Staphylococcus aureus genotypes may have acquired the staphylococcal cassette chromosome mec.