A1 Refereed original research article in a scientific journal

Bacterial adherence to self-reinforced polyglycolic acid and self-reinforced polylactic acid 96 urological spiral stents in vitro




AuthorsPétas A, Vuopio-Varkila J, Siitonen A, Välimaa T, Talja M, Taari K

Publication year1998

JournalBiomaterials

Journal name in sourceBiomaterials

Journal acronymBiomaterials

Volume19

Issue7-9

First page 677

Last page81

Number of pages5

ISSN0142-9612

DOIhttps://doi.org/10.1016/S0142-9612(97)00171-3


Abstract
The aim of this study was to evaluate the bacterial adherence to biodegradable self-reinforced polyglycolic acid (SR-PGA) and self-reinforced poly-DL-lactic acid (SR-PLA 96) spiral stents in vitro. They are used as temporary urethral stents in urology. Gold-plated metal wire, polyurethane and latex were used as controls. Materials were incubated up to 28 days in artificial urine, after which a bacterial suspension was added. After detaching by sonication the adhesive bacteria were analysed as colony forming units (CFUs) and by scanning electron microscopy (SEM) analysis. Adhesion was more significantly correlated to stent bacterial type than to the tested material in both assays. No encrustation was seen on SR-PGA or SR-PLA 96. SR-PGA and SR-PLA 96 had no effect on the bacterial growth. In conclusion, the bacterial properties are equally or more important than the material properties in the adhesion process.



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