Metabolic handling of C-13 labelled tripalmitin in healthy controls and patients with cystic fibrosis



: Murphy JL, Laiho KM, Jones AE, Wootton SA

Publisher: BRITISH MED JOURNAL PUBL GROUP

: 1998

 Archives of Disease in Childhood

: ARCHIVES OF DISEASE IN CHILDHOOD

: ARCH DIS CHILD

: 79

: 1

: 44

: 47

: 4

: 0003-9888

DOI: https://doi.org/10.1136/adc.79.1.44


Conclusion-Measurements of breath (CO2)-C-13 do not consistently reflect the gastrointestinal handling of emulsified C-13 labelled tripalmitin because of differences in digestion and absorption in cystic fibrosis. Further studies need to examine whether "breath tests" alone can predict with confidence the gastrointestinal handling of other C-13 labelled triglycerides and fatty acids.



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