A1 Refereed original research article in a scientific journal
Metabolic handling of C-13 labelled tripalmitin in healthy controls and patients with cystic fibrosis
Authors: Murphy JL, Laiho KM, Jones AE, Wootton SA
Publisher: BRITISH MED JOURNAL PUBL GROUP
Publication year: 1998
Journal: Archives of Disease in Childhood
Journal name in source: ARCHIVES OF DISEASE IN CHILDHOOD
Journal acronym: ARCH DIS CHILD
Volume: 79
Issue: 1
First page : 44
Last page: 47
Number of pages: 4
ISSN: 0003-9888
DOI: https://doi.org/10.1136/adc.79.1.44
Abstract
Conclusion-Measurements of breath (CO2)-C-13 do not consistently reflect the gastrointestinal handling of emulsified C-13 labelled tripalmitin because of differences in digestion and absorption in cystic fibrosis. Further studies need to examine whether "breath tests" alone can predict with confidence the gastrointestinal handling of other C-13 labelled triglycerides and fatty acids.
Conclusion-Measurements of breath (CO2)-C-13 do not consistently reflect the gastrointestinal handling of emulsified C-13 labelled tripalmitin because of differences in digestion and absorption in cystic fibrosis. Further studies need to examine whether "breath tests" alone can predict with confidence the gastrointestinal handling of other C-13 labelled triglycerides and fatty acids.