Branched-Chain and Aromatic Amino Acids Are Predictors of Insulin Resistance in Young Adults

: Wurtz P, Soininen P, Kangas AJ, Ronnemaa T, Lehtimaki T, Kahonen M, Viikari JS, Raitakari OT, Ala-Korpela M

Publisher: AMER DIABETES ASSOC

: 2013

: Diabetes Care

: DIABETES CARE

: 3

: 36

: 3

: 648

: 655

: 8

: 0149-5992

DOI: https://doi.org/10.2337/dc12-0895

CONCLUSIONS-Branched-chain and aromatic amino acids are markers of the development of insulin resistance in young, normoglycemic adults, with most pronounced associations for men. These findings suggest that the association of branched-chain and aromatic amino acids with the risk for future diabetes is at least partly mediated through insulin resistance. Diabetes Care 36:648-655,2013

Internal medicine