Infravesical obstruction in aromatase over expressing transgenic male mice with increased ratio of serum estrogen-to-androgen concentration



: Streng T, Li XD, Lehtoranta M, Makela S, Poutanen M, Talo A, Tekmal RR, Santti R

Publisher: LIPPINCOTT WILLIAMS & WILKINS

: 2002

Journal of Urology

JOURNAL OF UROLOGY

: J UROLOGY

: UNSP 0022-5347/02/1681-0298/0

: 168

: 1

: 298

: 302

: 5

: 0022-5347

DOI: https://doi.org/10.1016/S0022-5347(05)64911-7


Conclusions: Activation of the aromatase gene during an earlier developmental stage under the ubiquitin C promoter and highly elevated serum estrogen concentrations may explain the differences in voiding and prostate size in the AROM+ mouse strain.



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