Topical cis-urocanic acid attenuates oedema and erythema in acute and subacute skin inflammation in the mouse

: Laihia JK, Taimen P, Kujari H, Leino L

Publisher: WILEY-BLACKWELL

: 2012

: British Journal of Dermatology

: BRITISH JOURNAL OF DERMATOLOGY

: BRIT J DERMATOL

: 3

: 167

: 3

: 506

: 513

: 8

: 0007-0963

DOI: https://doi.org/10.1111/j.1365-2133.2012.11026.x

Conclusions The results suggest that cis-UCA - unlike hydrocortisone and tacrolimus - is efficient in both acute and subacute skin inflammation, attenuating skin oedema and erythema. Topical drug therapy with cis-UCA may provide a safe and effective drug treatment modality in inflammatory skin disorders.