Association of tumour necrosis factor a, b and c microsatellite polymorphisms with clinical disease activity and induction of remission in early rheumatoid arthritis - UTU Research Portal

A1 Refereed original research article in a scientific journal

Association of tumour necrosis factor a, b and c microsatellite polymorphisms with clinical disease activity and induction of remission in early rheumatoid arthritis

Authors: Laivoranta-Nyman S, Mottonen T, Hannonen P, Korpela M, Kautlainen H, Leirisalo-Repo M, Julkunen H, Luukkainen R, Hakala M, Vuori K, Laine AP, Toivanen A, Ilonen J

Publisher: CLINICAL & EXPER RHEUMATOLOGY CLINICAL & EXPER RHEUMATOLOGY

Publication year: 2006

Journal: Clinical and Experimental Rheumatology

Journal name in source: Association of tumour necrosis factor a, b and c microsatellite polymorphisms with clinical disease activity and induction of remission in early rheumatoid arthritis

Journal acronym: CLIN EXP RHEUMATOL

Volume: 24

Issue: 6

First page : 636

Last page: 642

Number of pages: 7

ISSN: 0392-856X

Abstract

Conclusion: Early TNFb1+ RA patients have more active disease but respond more favourably to COMBI treatment than the patients without this microsatellite allele. The finding may be of clinical relevance for the choice of DMARDs in early RA.