A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Bifidobacterium and Lactobacillus DNA in the human placenta
Tekijät: Satokari R, Grönroos T, Laitinen K, Salminen S, Isolauri E
Kustantaja: WILEY-BLACKWELL PUBLISHING, INC
Julkaisuvuosi: 2009
Lehti: Letters in Applied Microbiology
Tietokannassa oleva lehden nimi: LETTERS IN APPLIED MICROBIOLOGY
Lehden akronyymi: LETT APPL MICROBIOL
Vuosikerta: 48
Numero: 1
Aloitussivu: 8
Lopetussivu: 12
Sivujen määrä: 5
ISSN: 0266-8254
DOI: https://doi.org/10.1111/j.1472-765X.2008.02475.x
Tiivistelmä
Bacterial DNA contains unmethylated CpG oligodeoxynucleotide motifs which induce immune effects. Specific CpG motifs activate Toll-like receptor 9 and subsequently trigger Th-1-type immune responses. Although the newborn infant is considered immunologically immature, exposure by bacterial DNA may programme the infant's immune development during foetal life earlier than previously considered.
Bacterial DNA contains unmethylated CpG oligodeoxynucleotide motifs which induce immune effects. Specific CpG motifs activate Toll-like receptor 9 and subsequently trigger Th-1-type immune responses. Although the newborn infant is considered immunologically immature, exposure by bacterial DNA may programme the infant's immune development during foetal life earlier than previously considered.
Avainsanat:
bifidobacteria, CpG motif, DNA, immunity, lactobacilli, placenta
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