A1 Refereed original research article in a scientific journal

Neuroinflammation in Temporal Lobe Epilepsy Measured Using Positron Emission Tomographic Imaging of Translocator Protein



Authors: Gershen LD, Zanotti-Fregonara P, Dustin IH, Liow JS, Hirvonen J, Kreisl WC, Jenko KJ, Inati SK, Fujita M, Morse CL, Brouwer C, Hong JS, Pike VW, Zoghbi SS, Innis RB, Theodore WH

Publisher: Amer Medical Assoc

Publication year: 2015

Journal: JAMA Neurology

Journal name in source: JAMA NEUROLOGY

Journal acronym: Jama Neurol

Volume: 72

Issue: 8

First page : 882

Last page: 888

Number of pages: 7

ISSN: 2168-6149

DOI: https://doi.org/10.1001/jamaneurol.2015.0941(external)


Abstract

CONCLUSIONS AND RELEVANCE Binding of TSPO is increased both ipsilateral and contralateral to seizure foci in patients with TLE, suggesting ongoing inflammation. Anti-inflammatory therapy may play a role in treating drug-resistant epilepsy.




Last updated on 2024-26-11 at 18:51