A1 Refereed original research article in a scientific journal
The prognostic significance of declining health-related quality of life scores at 6 months after coronary artery bypass surgery
Authors: Gunn JM, Lautamäki AK, Hirvonen J, Kuttila KT
Publication year: 2014
Journal: QJM: An International Journal of Medicine
Journal acronym: QJM
Volume: 107
Issue: 5
First page : 369
Last page: 374
Number of pages: 6
ISSN: 1460-2725
DOI: https://doi.org/10.1093/qjmed/hct256(external)
Purpose: Health-related quality of life (HRQoL) measured on the EQ-5D (European quality of life-5 dimensions)-questionnaire has been shown to improve after coronary artery bypass grafting (CABG), this study investigated whether changes in HRQoL predict later morbidity.
METHODS:
Included were 404 consecutive patients undergoing isolated CABG between 2008 and 2010 who filled the EQ-5D-questionnaire at baseline and 6 months postoperatively. Records were reviewed for later major adverse cardiac and cerebrovascular events (MACCE) after 6 months. Follow-up was 38.6 months (10-58).
RESULTS:
Patients who suffered later MACCE more often had suffered an in-hospital postoperative stroke, had a longer in-hospital stay, had lower HRQoL scores at 6 months and deteriorated on several EQ-5D-subscales. Logistic regression showed 6 months visual analogue scale scores and declining function scores to be independent predictors of later MACCE.
CONCLUSION:
Deteriorating function and HRQoL-scores at 6 months as compared to baseline postoperatively predict later adverse cardiovascular events after CABG.