A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Microparticle - based platform for point-of-care immunoassays
Tekijät: Teppo Salminen, Etvi Juntunen, Merja Lahdenranta, Iida Martiskainen, Sheikh M. Talha, Kim Pettersson
Kustantaja: ACADEMIC PRESS INC ELSEVIER SCIENCE
Julkaisuvuosi: 2018
Journal: Analytical Biochemistry
Tietokannassa oleva lehden nimi: ANALYTICAL BIOCHEMISTRY
Lehden akronyymi: ANAL BIOCHEM
Vuosikerta: 548
Aloitussivu: 66
Lopetussivu: 68
Sivujen määrä: 3
ISSN: 0003-2697
eISSN: 1096-0309
DOI: https://doi.org/10.1016/j.ab.2018.02.021
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/31197303
There is a need for quantitative and sensitive, yet simple point-of-care immunoassays: We have developed a point-of-care microparticle-based immunoassay platform which combines the performance of a microliter well based assay with the usability of a rapid assay. The platform contained a separate reaction and detection chambers and microparticles for the solid-phase. Photoluminescent up-converting nanoparticles (UCNPs) were used as labels. The platform was tested with a cardiac troponin I assay, and a limit of detection of 19.7 ng/L was obtained. This study demonstrates the feasibility of developing point-of-care assays on the new platform for various analytes of interests.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
