A1 Refereed original research article in a scientific journal
Selective prescribing of simvastatin and atorvastatin by patient characteristics at treatment initiation over a 7-year period in Finland
Authors: Halava H, Helin-Salmivaara A, Junnila J, Huupponen R
Publisher: SPRINGER
Publication year: 2009
Journal: European Journal of Clinical Pharmacology
Journal name in source: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Journal acronym: EUR J CLIN PHARMACOL
Volume: 65
Issue: 9
First page : 927
Last page: 933
Number of pages: 7
ISSN: 0031-6970
DOI: https://doi.org/10.1007/s00228-009-0664-1
Channelling of atorvastatin over simvastatin toward the younger and healthier population was found during the first 4 years after its launch in Finland. Channelling may lead to confounding by indication, which must be taken into account when designing pharmacoepidemiology studies on statins.