Growth factor therapy and lymph node graft for lymphedema - UTU Research Portal

A1 Refereed original research article in a scientific journal

Growth factor therapy and lymph node graft for lymphedema

Authors: Tervala TV, Hartiala P, Tammela T, Visuri MT, Yla-Herttuala S, Alitalo K, Saarikko AM

Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE

Publication year: 2015

Journal: Journal of Surgical Research

Journal name in source: JOURNAL OF SURGICAL RESEARCH

Journal acronym: J SURG RES

Volume: 196

Issue: 1

First page : 200

Last page: 207

Number of pages: 8

ISSN: 0022-4804

DOI: https://doi.org/10.1016/j.jss.2015.02.031

Abstract

Conclusions: These results support our goal to treat secondary lymphedema by combining lymph node transfer with the growth factor therapy. VEGF-C provides the preferred alternative for growth factor therapy of lymphedema when compared with other VEGF-family growth factors, due to the superior lymphangiogenic response and minor blood vascular effects.