Uneven Braking Spins RNA Polymerase into a Pause
: Artsimovitch I, Belogurov GA
Publisher: CELL PRESS
: 2018
: Molecular Cell
: MOLECULAR CELL
: MOL CELL
: 69
: 5
: 723
: 725
: 4
: 1097-2765
: 1097-4164
DOI: https://doi.org/10.1016/j.molcel.2018.02.013
In this issue of Molecular Cell, Guo et al. (2018) and Kang et al. (2018) report structures of paused transcription complexes in which asynchronous translocation inhibits nucleotide addition, allowing for global rearrangements in RNA polymerase stabilized by RNA hairpin and NusA.