Schizophrenia and induced abortions: A national register-based follow-up study among Finnish women born between 1965-1980 with schizophrenia or schizoaffective disorder




Simoila L, Isometsä E, Gissler M, Suvisaari J, Sailas E, Halmesmäki E, Lindberg N

PublisherElsevier B.V.

2018

Schizophrenia Research

Schizophrenia Research

192

142

147

6

0920-9964

1573-2509

DOIhttps://doi.org/10.1016/j.schres.2017.05.039



Background: The objectives of this studywere to investigate, inwomenwith schizophrenia or schizoaffective disorder, the number and incidence of induced abortions (= pregnancy terminations performed by a physician), their demographic characteristics, use of contraceptives, plus indications of and complications related to pregnancy termination. Methods: Using the Care Register for Health Care, we identified Finnish women born between the years 1965–1980 whowere diagnosedwith either schizophrenia or schizoaffective disorder during the follow-up period ending 31.12.2013. For each case, five age- and place-of-birth- matched controlswere obtained fromthe Population Register of Finland. Information about births and induced abortions were obtained from the Medical Birth Register and the Induced Abortion Register.
Results: The number and incidence of induced abortions per 1000 follow-up years did not differ between cases and their controls. However, due to fewer pregnancies, cases exhibited an over 2-fold increased risk of pregnancy termination (RR 2.28; 95% CI 2.20–2.36). Cases were younger, were more often without a partner at the time of induced abortion, and their pregnancies resulted more often from a lack of contraception. Among cases, the indication for pregnancy termination was more often mother-to-be's medical condition. Induced abortions after 12weeks gestation were more common among cases. However, cases had nomore complications related to termination.Conclusions: The incidence of induced abortionsamong Finnishwomenwith schizophrenia or schizoaffective disorder is similar to the general population, but their risk per pregnancy over two-fold. They need effective, affordable family planning services and long-term premeditated contraception.



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