Information systems have a critical role in organizations. Practically all companies and organizations depend on information systems and their operations. Therefore, robustness and reliability are key issues in information systems and information systems infrastructures. Trustworthiness of technologies and systems is important, meaning that these need to be the goals of information systems management and development. In this article, we look at development of robustness of organization’s information systems infrastructure. The goal is to find the key issues that affect the infrastructure, impacting reliability and continuity of systems and technologies in the organization. Information systems need to be developed so that robustness and flexibility could be built into information systems and infrastructures. The goal is to develop systems that enable rather than restrict, so that systems act as a robust basis for activities and operations, and make it possible to reach for operative and strategic goals.