Impact of Lipid Measurements in Youth in Addition to Conventional Clinic-Based Risk Factors on Predicting Preclinical Atherosclerosis in Adulthood: The International Childhood Cardiovascular Cohort (i3C) Consortium - UTU Research Portal

A1 Refereed original research article in a scientific journal

Impact of Lipid Measurements in Youth in Addition to Conventional Clinic-Based Risk Factors on Predicting Preclinical Atherosclerosis in Adulthood: The International Childhood Cardiovascular Cohort (i3C) Consortium

Authors: Koskinen J, Juonala M, Dwyer T, Venn A, Thomson R, Bassano L, Berenson GS, Sabin Ma, Burns TL, Viikari JSA, Woo JG, Urbina EM, Prineas R, Hutri-Kähönen N, Sinaiko A, Jacobs D, Steinberger J, Danielts S, Raitakari OT, Magnussen CG

Publication year: 2018

Journal: Circulation

Volume: 137

Issue: 12

First page : 1246

Last page: 1255

Number of pages: 10

ISSN: 0009-7322

DOI: https://doi.org/10.1161/CIRCULATIONAHA.117.029726

Abstract

Conclusions—Non-laboratory-based risk factors and lipids measured in adolescence independently predicted preclinical atherosclerosis in young adulthood. The addition of lipid measurements to traditional clinic based risk factor assessment provided a statistically significant but clinically modest improvement on adolescent prediction of high cIMT in adulthood.