A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
MYC AMPLIFICATION - REGULATION OF MYC FUNCTION
Tekijät: KOSKINEN PJ, MAKELA TP, VASTRIK I, ALITALO K
Kustantaja: ELSEVIER SCIENCE BV
Julkaisuvuosi: 1993
Tietokannassa oleva lehden nimi: CLINICA CHIMICA ACTA
Lehden akronyymi: CLIN CHIM ACTA
Vuosikerta: 217
Numero: 1
Aloitussivu: 57
Lopetussivu: 62
Sivujen määrä: 6
ISSN: 0009-8981
DOI: https://doi.org/10.1016/0009-8981(93)90237-X
Tiivistelmä
The myc oncogenes have been implicated in the control of cell proliferation in both normal and neoplastic cells. There is increasing evidence that Myc proteins function as transcriptional regulators of other genes apparently involved in the control of cell proliferation. The effects of Myc on both gene expression and cell growth are differentially regulated by the recently described Max and DELTAMax proteins that can either cooperate or compete with Myc for sequence-specific DNA binding.
The myc oncogenes have been implicated in the control of cell proliferation in both normal and neoplastic cells. There is increasing evidence that Myc proteins function as transcriptional regulators of other genes apparently involved in the control of cell proliferation. The effects of Myc on both gene expression and cell growth are differentially regulated by the recently described Max and DELTAMax proteins that can either cooperate or compete with Myc for sequence-specific DNA binding.
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