B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä
DETERMINATION OF PK VALUES OF GUANOSINE NUCLEOTIDES AND NUCLEOSIDES AND RELATED-COMPOUNDS
Tekijät: LABADI I, LONNBERG H
Kustantaja: MAGYAR KEMIA FOLYOIRAT
Julkaisuvuosi: 1990
Lehti:: Magyar Kemiai Folyoirat
Tietokannassa oleva lehden nimi: MAGYAR KEMIAI FOLYOIRAT
Lehden akronyymi: MAGY KEM FOLY
Vuosikerta: 96
Numero: 11-12
Aloitussivu: 508
Lopetussivu: 514
Sivujen määrä: 7
ISSN: 0025-0155
Tiivistelmä
Protonation constants of the N1 atom of the guanine base and of the phosphate group were determined. Increase and corresponding decrease in the basicity of the N1 and phosphate group reflected intermolecular electrostatic interaction for the 5' isomers of the m7-guanosin nucleotides. A correlation has been found between the acid-base properties, conformation and the inhibition properties of these compounds in some kind of protein synthesis.
Protonation constants of the N1 atom of the guanine base and of the phosphate group were determined. Increase and corresponding decrease in the basicity of the N1 and phosphate group reflected intermolecular electrostatic interaction for the 5' isomers of the m7-guanosin nucleotides. A correlation has been found between the acid-base properties, conformation and the inhibition properties of these compounds in some kind of protein synthesis.
Turun yliopiston Tutkimustietojärjestelmän portaali