A1 Refereed original research article in a scientific journal

Rhinovirus Detection in Symptomatic and Asymptomatic Children: Value of Host Transcriptome Analysis



Authors: Heinonen S, Jartti T, Garcia C, Oliva S, Smitherman C, Anguiano E, de Steenhuijsen Piters WA, Vuorinen T, Ruuskanen O, Dimo B, Suarez NM, Pascual V, Ramilo O, Mejias A.

Publication year: 2016

Journal: American Journal of Respiratory and Critical Care Medicine

Volume: 193

Issue: 7

First page : 772

Last page: 782

Number of pages: 11

ISSN: 1073-449X

eISSN: 1535-4970

DOI: https://doi.org/10.1164/rccm.201504-0749OC


Abstract

Conclusions: Symptomatic RV infection induced a robust and reproducible transcriptional signature, whereas identification of RV in asymptomatic children was not associated with significant systemic transcriptional immune responses. Transcriptional profiling represents a useful tool to discriminate between active infection and incidental virus detection.



Last updated on 2024-26-11 at 16:45