Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer F-18-galacto-RGD in mouse atherosclerotic plaques




Saraste A, Laitinen I, Weidl E, Wildgruber M, Weber AW, Nekolla SG, Holzlwimmer G, Esposito I, Walch A, Leppanen P, Lisinen I, Luppa PB, Yla-Herttuala S, Wester HJ, Knuuti J, Schwaiger M

PublisherSPRINGER

2012

Journal of Nuclear Cardiology

JOURNAL OF NUCLEAR CARDIOLOGY

J NUCL CARDIOL

4

19

4

775

784

10

1071-3581

DOIhttps://doi.org/10.1007/s12350-012-9554-5



Uptake of F-18-galacto-RGD in mouse atherosclerotic lesions was reduced by lipid-lowering diet intervention. Expression of αvβ3 integrin is a potential target for evaluation of therapy response in atherosclerosis.



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