Maternal diabetes induces changes in the umbilical cord gene expression




Koskinen A, Lehtoranta L, Laiho A, Laine J, Kaapa P, Soukka H

PublisherW B SAUNDERS CO LTD

2015

Placenta

PLACENTA

PLACENTA

36

7

767

774

8

0143-4004

DOIhttps://doi.org/10.1016/j.placenta.2015.04.004(external)



Discussion: Maternal diabetic environment seems to alter umbilical cord expression of genes involved in the regulation of vascular development and function with simultaneous umbilical vessel muscle layer thickening. These alterations suggest vascular phenotypic modifications, which in turn may lead to long-term vascular consequences in various tissues in infants of diabetic mothers. (C) 2015 Elsevier Ltd. All rights reserved.




Last updated on 2024-26-11 at 14:59