A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Hydroxyapatite and bioactive glass surfaces for fiber reinforced composite implants via surface ablation by Excimer laser
Tekijät: Kulkova J, Moritz N, Huhtinen H, Mattila R, Donati I, Marsich E, Paoletti S, Vallittu PK
Kustantaja: ELSEVIER SCIENCE BV
Julkaisuvuosi: 2017
Journal: Journal of the Mechanical Behavior of Biomedical Materials
Tietokannassa oleva lehden nimi: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
Lehden akronyymi: J MECH BEHAV BIOMED
Vuosikerta: 75
Aloitussivu: 89
Lopetussivu: 96
Sivujen määrä: 8
ISSN: 1751-6161
eISSN: 1878-0180
DOI: https://doi.org/10.1016/j.jmbbm.2017.07.005
Tiivistelmä
In skeletal reconstructions, composites, such as bisphenol-A-glycidyldimethacrylate resin reinforced with glass fibers, are potentially useful alternatives to metallic implants. Recently, we reported a novel method to prepare bioactive surfaces for these composites. Surface etching by Excimer laser was used to expose bioactive glass granules embedded in the resin. The purpose of this study was to analyze two types of bioactive surfaces created by this technique. The surfaces contained bioactive glass and hydroxyapatite granules.The selected processing parameters were adequate for the creation of the surfaces. However, the use of porous hydroxyapatite prevented the complete exposure the granules. In cell culture, for bioactive glass coatings, the pattern of proliferation of MG63 cells was comparable to that in the positive control group (Ti6A14V) while inferior cell proliferation was observed on the surfaces containing hydroxyapatite granules. Scanning electron microscopy revealed osteointegration of implants with both types of surfaces.The technique is suitable for the exposure of solid bioactive glass granules. However, the long-term performance of the surfaces needs further assessment.
In skeletal reconstructions, composites, such as bisphenol-A-glycidyldimethacrylate resin reinforced with glass fibers, are potentially useful alternatives to metallic implants. Recently, we reported a novel method to prepare bioactive surfaces for these composites. Surface etching by Excimer laser was used to expose bioactive glass granules embedded in the resin. The purpose of this study was to analyze two types of bioactive surfaces created by this technique. The surfaces contained bioactive glass and hydroxyapatite granules.The selected processing parameters were adequate for the creation of the surfaces. However, the use of porous hydroxyapatite prevented the complete exposure the granules. In cell culture, for bioactive glass coatings, the pattern of proliferation of MG63 cells was comparable to that in the positive control group (Ti6A14V) while inferior cell proliferation was observed on the surfaces containing hydroxyapatite granules. Scanning electron microscopy revealed osteointegration of implants with both types of surfaces.The technique is suitable for the exposure of solid bioactive glass granules. However, the long-term performance of the surfaces needs further assessment.
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