A1 Refereed original research article in a scientific journal

HLA-DPB1(star)04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study




AuthorsDavid Hadley, William Hagopian, Edwin Liu, Jin-Xiong She, Olli Simell, Beena Akolkar, Anette-G. Ziegler, Marian Rewers, Jeffrey P. Krischer, Wei-Min Chen, Suna Onengut-Gumuscu, Teodorica L. Bugawan, Stephen S. Rich, Henry Erlich, Daniel Agardh and the TEDDY Study Group

PublisherNATURE PUBLISHING GROUP

Publication year2015

Journal:American Journal of Gastroenterology

Journal name in sourceAMERICAN JOURNAL OF GASTROENTEROLOGY

Journal acronymAM J GASTROENTEROL

Volume110

Issue6

First page 915

Last page920

Number of pages6

ISSN0002-9270

eISSN1572-0241

DOIhttps://doi.org/10.1038/ajg.2015.150


Abstract

CONCLUSIONS: HLA-DPB1(star)04:01 may reduce the risk of tTGAs, an early marker of CD, among DR3-DQ2 children, confirming that additional variants in the HLA region influence the risk for CDA.




Last updated on 2024-26-11 at 22:57