A1 Refereed original research article in a scientific journal
HLA-DPB1(star)04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study
Authors: David Hadley, William Hagopian, Edwin Liu, Jin-Xiong She, Olli Simell, Beena Akolkar, Anette-G. Ziegler, Marian Rewers, Jeffrey P. Krischer, Wei-Min Chen, Suna Onengut-Gumuscu, Teodorica L. Bugawan, Stephen S. Rich, Henry Erlich, Daniel Agardh and the TEDDY Study Group
Publisher: NATURE PUBLISHING GROUP
Publication year: 2015
Journal: American Journal of Gastroenterology
Journal name in source: AMERICAN JOURNAL OF GASTROENTEROLOGY
Journal acronym: AM J GASTROENTEROL
Volume: 110
Issue: 6
First page : 915
Last page: 920
Number of pages: 6
ISSN: 0002-9270
eISSN: 1572-0241
DOI: https://doi.org/10.1038/ajg.2015.150
CONCLUSIONS: HLA-DPB1(star)04:01 may reduce the risk of tTGAs, an early marker of CD, among DR3-DQ2 children, confirming that additional variants in the HLA region influence the risk for CDA.