A1 Refereed original research article in a scientific journal

HLA-DPB1(star)04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study




AuthorsDavid Hadley, William Hagopian, Edwin Liu, Jin-Xiong She, Olli Simell, Beena Akolkar, Anette-G. Ziegler, Marian Rewers, Jeffrey P. Krischer, Wei-Min Chen, Suna Onengut-Gumuscu, Teodorica L. Bugawan, Stephen S. Rich, Henry Erlich, Daniel Agardh and the TEDDY Study Group

PublisherNATURE PUBLISHING GROUP

Publication year2015

JournalAmerican Journal of Gastroenterology

Journal name in sourceAMERICAN JOURNAL OF GASTROENTEROLOGY

Journal acronymAM J GASTROENTEROL

Volume110

Issue6

First page 915

Last page920

Number of pages6

ISSN0002-9270

eISSN1572-0241

DOIhttps://doi.org/10.1038/ajg.2015.150


Abstract

CONCLUSIONS: HLA-DPB1(star)04:01 may reduce the risk of tTGAs, an early marker of CD, among DR3-DQ2 children, confirming that additional variants in the HLA region influence the risk for CDA.




Last updated on 2024-26-11 at 22:57