A1 Refereed original research article in a scientific journal
PET/CT Imaging of Integrin alpha v beta 3 Expression in Human Carotid Atherosclerosis
Authors: Ambros J. Beer, Jaroslav Pelisek, Peter Heider, Antti Saraste, Christian Reeps, Stephan Metz, Stefan Seidl, Horst Kessler, Hans-Jürgen Wester, Hans Henning Eckstein, Markus Schwaiger
Publisher: ELSEVIER SCIENCE INC
Publication year: 2014
Journal: JACC: Cardiovascular Imaging
Journal name in source: JACC-CARDIOVASCULAR IMAGING
Journal acronym: JACC-CARDIOVASC IMAG
Volume: 7
Issue: 2
First page : 178
Last page: 187
Number of pages: 10
ISSN: 1936-878X
DOI: https://doi.org/10.1016/j.jcmg.2013.12.003
CONCLUSIONS [F-18]Galacto-RGD PET/CT shows specific tracer accumulation in human atherosclerotic carotid plaques, which correlates with alpha v beta 3 expression. Based on these initial data, larger prospective studies are now warranted to evaluate the potential of molecular imaging of alpha v beta 3 expression for assessment of plaque inflammation in patients. (J Am Coll Cardiol Img 2014;7:178-87) (C) 2014 by the American College of Cardiology Foundation