A1 Refereed original research article in a scientific journal

PET/CT Imaging of Integrin alpha v beta 3 Expression in Human Carotid Atherosclerosis




AuthorsAmbros J. Beer, Jaroslav Pelisek, Peter Heider, Antti Saraste, Christian Reeps, Stephan Metz, Stefan Seidl, Horst Kessler, Hans-Jürgen Wester, Hans Henning Eckstein, Markus Schwaiger

PublisherELSEVIER SCIENCE INC

Publication year2014

JournalJACC: Cardiovascular Imaging

Journal name in sourceJACC-CARDIOVASCULAR IMAGING

Journal acronymJACC-CARDIOVASC IMAG

Volume7

Issue2

First page 178

Last page187

Number of pages10

ISSN1936-878X

DOIhttps://doi.org/10.1016/j.jcmg.2013.12.003


Abstract

CONCLUSIONS [F-18]Galacto-RGD PET/CT shows specific tracer accumulation in human atherosclerotic carotid plaques, which correlates with alpha v beta 3 expression. Based on these initial data, larger prospective studies are now warranted to evaluate the potential of molecular imaging of alpha v beta 3 expression for assessment of plaque inflammation in patients. (J Am Coll Cardiol Img 2014;7:178-87) (C) 2014 by the American College of Cardiology Foundation




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