A1 Journal article – refereed

Telomere length and antioxidant defense associate with parasite-induced retarded growth in wild brown trout




List of Authors: Stauffer Janina, Bruneaux Matthieu, Panda Bineet, Visse Marko, Vasemägi Anti, Ilmonen Petteri

Publisher: Springer Verlag

Publication year: 2017

Journal: Oecologia

Journal name in source: Oecologia

Volume number: 185

Issue number: 3

Number of pages: 10

ISSN: 0029-8549

eISSN: 1432-1939

DOI: http://dx.doi.org/10.1007/s00442-017-3953-x


Abstract

Early growth conditions can have profound impacts on individuals’ development, growth and physiology, with subsequent long-term consequences for individuals’ fitness and life expectancy. Telomere length (TL) has been suggested to indicate both individual fitness and life expectancy in wide range of species, as the telomere attrition rate at early age can be accelerated due to exposure to various stressors, including parasites and inflammatory diseases, which increase production of reactive oxygen species (ROS) and influence antioxidant (AO) levels. We investigated impacts of Tetracapsuloides bryosalmonae infection, a causative agent of proliferative kidney disease (PKD), on AO status and TL in a natural population of juvenile brown trout (Salmo trutta). The fish with higher parasite load showed more severe kidney hyperplasia, anemia and smaller body size compared to less parasitized fish. Furthermore, fish with severe PKD symptoms had lower SOD-, CAT- and GST activity than fish with milder kidney hyperplasia. However, parasite load was not directly correlated either with AOs or with TL. Smaller fish showed shorter TLs, potentially reflecting lower individual quality. The fish, which were less sensitive to parasite-induced impaired growth, quantified as parasite load-adjusted fork length, showed also longer TLs, lower GR- and GST activity and less GSHtot compared to more sensitive fish. These results provide novel knowledge about the impacts of the PKD in brown trout at the molecular level and support the idea that TL may reflect individual quality and ability to cope with parasitic infections.


Last updated on 2021-24-06 at 11:56