A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Respiratory viral infections among children with community-acquired pneumonia and pleural effusion




TekijätNascimento-Carvalho CM, Oliveira JR, Cardoso MA, Araujo-Neto C, Barral A, Saukkoriipi A, Paldanius M, Leinonen M, Lappalainen M, Soderlund-Venermo M, Vainionpaa R, Ruuskanen O

KustantajaINFORMA HEALTHCARE

KustannuspaikkaLONDON; TELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND

Julkaisuvuosi2013

JournalScandinavian Journal of Infectious Diseases

Tietokannassa oleva lehden nimiScandinavian Journal of Infectious Diseases

Lehden akronyymiScand.J.Infect.Dis.

Numero sarjassa6

Vuosikerta45

Numero6

Aloitussivu478

Lopetussivu483

Sivujen määrä6

ISSN0036-5548

DOIhttps://doi.org/10.3109/00365548.2012.754106


Tiivistelmä
Pleural effusion (PE), a complication of community-acquired pneumonia (CAP), is usually attributed to a bacterial infection. Nonetheless, viral infections have not been investigated routinely. We searched for bacterial and viral infections among 277 children hospitalized with CAP. Among these children 206 (74%) had radiographic confirmation, of whom 25 (12%) had PE. The aetiology was established in 18 (72%) PE cases: bacterial (n = 5; 28%), viral (n = 9; 50%), and viral-bacterial (n = 4; 22%) infections were found. Infection by rhinovirus (n = 3), enterovirus, Streptococcus pneumoniae (n = 2 each), Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, influenza A virus, and respiratory syncytial virus (RSV)(n = 1 each) were detected as probable sole infections. Parainfluenza virus 1/3 + influenza A virus and RSV + influenza A virus (n = 1 each) were identified as mixed viral-viral infections. Probable viral non-bacterial infection was identified in a third of the cases with CAP and PE. It is advisable to investigate viral as well as bacterial infections among children with CAP and PE.



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