A1 Refereed original research article in a scientific journal

New times, new trends for ethionamide: In vitro evaluation of drug-loaded thermally carbonized porous silicon microparticles




AuthorsVale N, Makila E, Salonen J, Gomes P, Hirvonen J, Santos HA

PublisherELSEVIER SCIENCE BV

Publication year2012

Journal:European Journal of Pharmaceutics and Biopharmaceutics

Journal name in sourceEUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Journal acronymEUR J PHARM BIOPHARM

Number in series2

Volume81

Issue2

First page 314

Last page323

Number of pages10

ISSN0939-6411

DOIhttps://doi.org/10.1016/j.ejpb.2012.02.017


Abstract
In addition, new thiolated metabolites were identified from incubation of ETA-loaded PSi with HepG2 liver cells, which opens new perspectives toward both the understanding of ETA metabolism and the development of novel ETA-based systems with improved efficacy against MDR-TB. (C) 2012 Elsevier B.V. All rights reserved.



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