Quality of life in treated patients with acromegaly



: Kauppinen-Makelin R, Sane T, Sintonen H, Markkanen H, Valimaki MJ, Loyttyniemi E, Niskanen L, Reunanen A, Stenman UH

Publisher: ENDOCRINE SOC

: 2006

: Journal of Clinical Endocrinology and Metabolism

: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

: J CLIN ENDOCR METAB

: 91

: 10

: 3891

: 3896

: 6

: 0021-972X

DOI: https://doi.org/10.1210/jc.2006-0676


Conclusions: HRQoL is reduced in treated patients with acromegaly. The best HRQoL may be achieved by normalization of IGF-I and by targeting the GHOGTT nadir to levels between 0.3 and 1.0 mu g/liter. Radiotherapy is associated with adverse HRQoL.



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