A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Catalytically significant macrochelate formation in Zn2+ promoted hydrolysis of oligoribonucleotides: Model studies with chimeric phosphodiester/methylphosphonate oligomers
Tekijät: Kuusela S, Lonnberg H
Kustantaja: MARCEL DEKKER INC
Julkaisuvuosi: 1998
Journal: Nucleosides & nucleotides
Tietokannassa oleva lehden nimi: NUCLEOSIDES & NUCLEOTIDES
Lehden akronyymi: NUCLEOS NUCLEOT
Vuosikerta: 17
Numero: 12
Aloitussivu: 2417
Lopetussivu: 2427
Sivujen määrä: 11
ISSN: 0732-8311
DOI: https://doi.org/10.1080/07328319808004328
Tiivistelmä
The kinetics of Zn2+ promoted hydrolysis of chimeric oligonucleotides Up[Tp(Me)](3)T and Up[Tp(Me)](3)Tp was studied. The results were compared to those obtained with corresponding phosphodiester oligonucleotides, and discussed in terms of an oligonucleotide-metal ion macrochelate formation.
The kinetics of Zn2+ promoted hydrolysis of chimeric oligonucleotides Up[Tp(Me)](3)T and Up[Tp(Me)](3)Tp was studied. The results were compared to those obtained with corresponding phosphodiester oligonucleotides, and discussed in terms of an oligonucleotide-metal ion macrochelate formation.
Turun yliopiston Tutkimustietojärjestelmän portaali