[F-18]FDG Accumulation in Early Coronary Atherosclerotic Lesions in Pigs



: Miikka Tarkia, Antti Saraste, Christoffer Stark, Tommi Vähäsilta, Timo Savunen, Marjatta Strandberg, Virva Saunavaara, Tuula Tolvanen, Jarmo Teuho, Mika Teräs, Olli Metsälä, Petteri Rinne, Ilkka Heinonen, Nina Savisto, Mikko Pietilä, Pekka Saukko, Anne Roivainen, Juhani Knuuti

Publisher: PUBLIC LIBRARY SCIENCE

: 2015

: PLoS ONE

: PLOS ONE

: PLOS ONE

: ARTN e0131332

: 10

: 6

: 15

: 1932-6203

DOI: https://doi.org/10.1371/journal.pone.0131332


We found increased uptake of [F-18]FDG in coronary atherosclerotic lesions in a pig model. However, uptake in these early stage lesions was not detectable with in vivo PET imaging. Further studies are needed to clarify whether visible [F-18]FDG uptake in coronary arteries represents more advanced, highly inflamed plaques.


Last updated on 2024-26-11 at 13:59