A1 Refereed original research article in a scientific journal
[F-18]FDG Accumulation in Early Coronary Atherosclerotic Lesions in Pigs
Authors: Miikka Tarkia, Antti Saraste, Christoffer Stark, Tommi Vähäsilta, Timo Savunen, Marjatta Strandberg, Virva Saunavaara, Tuula Tolvanen, Jarmo Teuho, Mika Teräs, Olli Metsälä, Petteri Rinne, Ilkka Heinonen, Nina Savisto, Mikko Pietilä, Pekka Saukko, Anne Roivainen, Juhani Knuuti
Publisher: PUBLIC LIBRARY SCIENCE
Publication year: 2015
Journal: PLoS ONE
Journal name in source: PLOS ONE
Journal acronym: PLOS ONE
Article number: ARTN e0131332
Volume: 10
Issue: 6
Number of pages: 15
ISSN: 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0131332
We found increased uptake of [F-18]FDG in coronary atherosclerotic lesions in a pig model. However, uptake in these early stage lesions was not detectable with in vivo PET imaging. Further studies are needed to clarify whether visible [F-18]FDG uptake in coronary arteries represents more advanced, highly inflamed plaques.
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