A1 Refereed original research article in a scientific journal

Effect of voriconazole on the pharmacokinetics and pharmacodynamics of zolpidem in healthy subjects



Authors: Saari TI, Laine K, Leino K, Valtonen M, Neuvonen PJ, Olkkola KT

Publisher: BLACKWELL PUBLISHING

Publication year: 2007

Journal: British Journal of Clinical Pharmacology

Journal name in source: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Journal acronym: BRIT J CLIN PHARMACO

Volume: 63

Issue: 1

First page : 116

Last page: 120

Number of pages: 5

ISSN: 0306-5251

DOI: https://doi.org/10.1111/j.1365-2125.2006.02707.x


Abstract
Conclusion: Voriconazole caused a moderate increase in exposure to zolpidem in healthy young subjects but no clear pharmacodynamic changes were observed between the groups.


Keywords:
CYP3A4, cytochrome P450, drug interaction, voriconazole, zolpidem

Downloadable publication

This is an electronic reprint of the original article.
This reprint may differ from the original in pagination and typographic detail. Please cite the original version.


Last updated on 26/11/2024 09:36:17 PM