Analgesic use before and after oral anticoagulant initiation-a population-based study in Finland - UTU Research Portal

A1 Refereed original research article in a scientific journal

Analgesic use before and after oral anticoagulant initiation-a population-based study in Finland

Authors: Ilomaki J, Helin-Salmivaara A, Huupponen R, Rikala M, Kirkpatrick CM, Korhonen MJ

Publisher: SPRINGER HEIDELBERG

Publication year: 2015

Journal: European Journal of Clinical Pharmacology

Journal name in source: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Journal acronym: EUR J CLIN PHARMACOL

Volume: 71

Issue: 6

First page : 723

Last page: 732

Number of pages: 10

ISSN: 0031-6970

DOI: https://doi.org/10.1007/s00228-015-1836-9

Abstract

The use of NSAIDs decreases extensively among warfarin initiators which is encouraging. However, the use of NSAIDs increases among rivaroxaban and dabigatran initiators. This is a concern as the bleeding risk may increase due to potential pharmacodynamic interactions.