A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis



: Kainulainen V, Sundvall M, Määttä JA, Santiestevan E, Klagsbrun M, Elenius K

Publisher: ASBMB

: UNITED STATES

: 2000

: The Journal of biological chemistry

: J.Biol.Chem.

: 275

: 12

: 8641

: 8649




Adaptor Proteins, Signal Transducing, Apoptosis, Cell Division/physiology, Cell Survival/physiology, Chemotaxis/physiology, Mitogen-Activated Protein Kinases/metabolism, Neuregulin-1/metabolism, Phosphatidylinositol 3-Kinases/metabolism, Protein Isoforms/metabolism, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins/metabolism, Receptor, Epidermal Growth Factor/metabolism, Shc Signaling Adaptor Proteins, Signal Transduction



Last updated on 26/11/2024 09:47:06 PM