A1 Refereed original research article in a scientific journal

Preclinical imaging of kallikrein-related peptidase 2 (hK2) in prostate cancer with a In-111-radiolabelled monoclonal antibody, 11B6




AuthorsTimmermand OV, Ulmert D, Evans-Axelsson S, Pettersson K, Bjartell A, Lilja H, Strand SE, Tran TA

PublisherSPRINGER HEIDELBERG

Publication year2014

JournalEJNMMI Research

Journal name in sourceEJNMMI RESEARCH

Journal acronymEJNMMI RES

Article numberARTN 51

Volume4

Number of pages12

ISSN2191-219X

DOIhttps://doi.org/10.1186/s13550-014-0051-5


Abstract

Conclusions: Our study demonstrates the potential of In-111-DTPA-11B6 for the detection of metastatic prostate cancer and monitoring anti-androgen therapy, as it exhibits an increased uptake and accumulation in viable tumour when compared to normal tissue. A humanised version of the 11B6 monoclonal antibody is currently under evaluation.




Last updated on 2024-26-11 at 14:12