Refereed journal article or data article (A1)

The A1330V polymorphism of the low-density lipoprotein receptor-related protein 5 gene (LRP5) associates with low peak bone mass in young healthy men

List of Authors: Saarinen A, Valimaki VV, Valimaki MJ, Loyttyniemi E, Auro K, Uusen P, Kuris M, Lehesjoki AE, Makitie O


Publication year: 2007

Journal: BONE

Journal name in source: BONE

Journal acronym: BONE

Volume number: 40

Issue number: 4

Number of pages: 7

ISSN: 8756-3282


Conclusion: The polymorphic valine variant at position 1330 of LRP5 was significantly associated with reduced BMC and BMD values in healthy young Finnish men. The results provide evidence for the crucial role of LRP5 in peak bone mass acquisition. (c) 2006 Elsevier Inc. All rights reserved.

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