A1 Refereed original research article in a scientific journal
Temperament trait Harm Avoidance associates with mu-opioid receptor availability in frontal cortex: A PET study using [C-11]carfentanil
Authors: Tuominen L, Salo J, Hirvonen J, Nagren K, Laine P, Melartin T, Isometsa E, Viikari J, Raitakari O, Keltikangas-Jarvinen L, Hietala J
Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE
Publication year: 2012
Journal: NeuroImage
Journal name in source: NEUROIMAGE
Journal acronym: NEUROIMAGE
Number in series: 3
Volume: 61
Issue: 3
First page : 670
Last page: 676
Number of pages: 7
ISSN: 1053-8119
DOI: https://doi.org/10.1016/j.neuroimage.2012.03.063(external)
Abstract
In conclusion, higher Harm Avoidance score in healthy subjects is associated with higher p-opioid availability in regions involved in the regulation of anxiety as well as in the control of emotions, affective component of pain and interoceptive awareness. The results have relevance in the research of vulnerability factors for affective disorders. (c) 2012 Elsevier Inc. All rights reserved.
In conclusion, higher Harm Avoidance score in healthy subjects is associated with higher p-opioid availability in regions involved in the regulation of anxiety as well as in the control of emotions, affective component of pain and interoceptive awareness. The results have relevance in the research of vulnerability factors for affective disorders. (c) 2012 Elsevier Inc. All rights reserved.