Diagnostic methods for and clinical pictures of polyomavirus primary infections in children, Finland.




Tingting Chen, Laura Tanner, Ville Simell, Lea Hedman, Marjaana Mäkinen, Mohammadreza Sadeghi, Riitta Veijola, Heikki Hyöty, Jorma Ilonen, Mikael Knip, Jorma Toppari, Olli Simell, Maria Söderlund-Venermo, Klaus Hedman

2014

Emerging Infectious Diseases

Emerging infectious diseases

Emerg Infect Dis

20

4

689

692

4

1080-6059

DOIhttps://doi.org/10.3201/eid2004.131015



We used comprehensive serodiagnostic methods (IgM, IgG, and IgG avidity) and PCR to study Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus infections in children observed from infancy to adolescence. Comparing seroconversion intervals with previous and subsequent intervals, we found that primary infections with these 2 viruses were asymptomatic in childhood.




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