Brain acetylcholinesterase activity impairment and early Alzheimer's in mild cognitive disease
: Rinne JO, Kaasinen V, Jarvenpaa T, Nagren K, Roivainen A, Yu M, Oikonen V, Kurki T
Publisher: BRITISH MED JOURNAL PUBL GROUP
: 2003
: Journal of Neurology, Neurosurgery and Psychiatry
: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
: J NEUROL NEUROSUR PS
: 74
: 1
: 113
: 115
: 3
: 0022-3050
DOI: https://doi.org/10.1136/jnnp.74.1.113(external)
Conclusions: Hippocampal acetylcholinesterase activity is only slightly reduced in mild cognitive impairment and early Alzheimer's disease and so the value of in vivo acetylcholinesterase measurements in detecting the early Alzheimer process is limited.