Acetaminophen Improves Analgesia but Does Not Reduce Opioid Requirement After Major Spine Surgery in Children and Adolescents

: HILLER A, HELENIUS I, NURMI E, NEUVONEN PJ, Kaukonen M, HARTIKAINEN T, KORPELA R, TAIVAINEN T, MERETOJA OA

Publisher: LIPPINCOTT WILLIAMS & WILKINS

: 2012

Spine

: SPINE

: 20

: 37

: 20

: E1225

: E1231

: 7

: 0362-2436

DOI: https://doi.org/10.1097/BRS.0b013e318263165c

Conclusion. IV-administered acetaminophen 90 mg/kg/day, adjuvant to oxycodone, did improve analgesia, but did not diminish oxycodone consumption during 24 hours after major spine surgery in children and adolescents. All acetaminophen concentrations were in nontoxic levels.

acetaminophen, adolescents, children, idiopathic scoliosis, posterior spinal fusion and instrumentation, spondylolisthesis