Acetaminophen Improves Analgesia but Does Not Reduce Opioid Requirement After Major Spine Surgery in Children and Adolescents - UTU Research Portal

A1 Refereed original research article in a scientific journal

Acetaminophen Improves Analgesia but Does Not Reduce Opioid Requirement After Major Spine Surgery in Children and Adolescents

Authors: HILLER A, HELENIUS I, NURMI E, NEUVONEN PJ, Kaukonen M, HARTIKAINEN T, KORPELA R, TAIVAINEN T, MERETOJA OA

Publisher: LIPPINCOTT WILLIAMS & WILKINS

Publication year: 2012

Journal: Spine

Journal name in source: SPINE

Journal acronym: SPINE

Number in series: 20

Volume: 37

Issue: 20

First page : E1225

Last page: E1231

Number of pages: 7

ISSN: 0362-2436

DOI: https://doi.org/10.1097/BRS.0b013e318263165c(external)

Abstract

Conclusion. IV-administered acetaminophen 90 mg/kg/day, adjuvant to oxycodone, did improve analgesia, but did not diminish oxycodone consumption during 24 hours after major spine surgery in children and adolescents. All acetaminophen concentrations were in nontoxic levels.