A1 Refereed original research article in a scientific journal
Acetaminophen Improves Analgesia but Does Not Reduce Opioid Requirement After Major Spine Surgery in Children and Adolescents
Authors: HILLER A, HELENIUS I, NURMI E, NEUVONEN PJ, Kaukonen M, HARTIKAINEN T, KORPELA R, TAIVAINEN T, MERETOJA OA
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Publication year: 2012
Journal: Spine
Journal name in source: SPINE
Journal acronym: SPINE
Number in series: 20
Volume: 37
Issue: 20
First page : E1225
Last page: E1231
Number of pages: 7
ISSN: 0362-2436
DOI: https://doi.org/10.1097/BRS.0b013e318263165c
Conclusion. IV-administered acetaminophen 90 mg/kg/day, adjuvant to oxycodone, did improve analgesia, but did not diminish oxycodone consumption during 24 hours after major spine surgery in children and adolescents. All acetaminophen concentrations were in nontoxic levels.
Keywords:
acetaminophen, adolescents, children, idiopathic scoliosis, posterior spinal fusion and instrumentation, spondylolisthesis